Synergistic effect of a mixture of Frankenia Florida (L chevall) plant extract with some antibiotics against some pathogenic bacterial species
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Abstract
The purpose of this study is to investigate and evaluate the antibacterial activities of Frankenia Florida (L chevall) extracts (ethanol/water) against four strains of bacteria: Escherichia coli (ATCC 25922), Staphylococcus aureus(ATTC 25923) Bacillus Cereus and Condida Albicans using the diffusion method. The results revealed that all extracts have a certain biological activity against gram-negative and Gram-positive bacteria at 1000 and 5000 g/ml. In addition, the extracts (ethanol/water) showed the highest activity, is against Pseudomonas aeruginosa. The combination of Frankenia Florida (L chevall) with each of the standard antibiotics: Co-trimoxazole ( COT 25µg ), Metromidazole ( MT5µg ), Amikacin ( AK30µg ) Amoxicillin (AMX 25µg ), Cefazoline ( CZ 30µg ). They were more active and showed significant synergistic effects, extracts (ethanol/water) of medicinal plants Frankenia Florida (L chevall), It also showed strong synergistic effects. The results of this study suggest that Frankenia Florida (L chevall) be used to treat diseases caused by the organisms studied. Further, pharmacological and chemical studies can be carried out in order to isolate and identify the chemical constituents responsible for antimicrobial activity in selected plants.
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